Weekly Roundup for FEBRUARY 7, 2020: Recent Publications in Women’s Mental Health

By | February 10, 2020

Perinatal depressive symptoms often start in the prenatal rather than postpartum period: results from a longitudinal study.

Wilcox M, McGee BA, Ionescu DF, Leonte M, LaCross L, Reps J, Wildenhaus K.  Arch Womens Ment Health. 2020 Feb 4. 

Nearly 10% of women entered the pregnancy with depressive symptoms’ the prevalence increased to 16% in the third trimester.  The prevalence of depressive symptoms was about the same at 4 weeks and 3 months postpartum. Among women with postpartum depressive symptoms, 80% of the episodes occurred during pregnancy, with 1/3 occurring in the first trimester. 


Perinatal Mixed Affective State: Wherefore Art Thou?

Koukopoulos AE, Angeletti G, Sani G, Janiri D, Manfredi G, Kotzalidis GD, De Chiara L.  Psychiatr Clin North Am. 2020 Mar;43(1):113-126. 

Mixed states in patients with a perinatal mood episode is seldom encountered. Lack of appropriate assessment tools could be partly responsible for this observation.  


Changes in quality of life and sleep across the perinatal period in women with mood disorders.

Kang AW, Pearlstein TB, Sharkey KM.  Qual Life Res. 2020 Feb 3. 

In this sample of women with depression and/or anxiety, quality of life was related to postpartum depressive symptoms, but not to objectively measured sleep quality, quantity, or timing.


Recovery from postpartum psychosis: a systematic review and metasynthesis of women’s and families’ experiences.

Forde R, Peters S, Wittkowski A.  Arch Womens Ment Health. 2020 Feb 4. 

Four main themes incorporating 13 subthemes were identified following synthesis: (1) Experiencing the unspeakable, (2) Loss and disruption, (3) Realigning old self and new self and the integrative theme of (4) Social context.


Pharmacologic labour analgesia and its relationship to postpartum psychiatric disorders: a scoping review.

Munro A, MacCormick H, Sabharwal A, George RB.  Can J Anaesth. 2020 Feb 4.

Most studies relied on screening tests for diagnosing postpartum psychiatric illness and did not assess the impact of labor analgesia on postpartum psychiatric illness as the primary study objective.  More study is needed to better understand the impact of labor analgesia on risk for postpartum psychiatric illness.  


Epidural Labor Analgesia Is Associated with a Decreased Risk of the Edinburgh Postnatal Depression Scale in Trial of Labor after Cesarean: A Multicenter, Prospective Cohort Study.

Sun J, Xiao Y, Zou L, Liu D, Huang T, Zheng Z, Yan X, Yuan A, Li Y, Huang X.

Biomed Res Int. 2020 Jan 16.   Free Article

At 48 hours, women who had received epidural analgesia were less likely to have Edinburgh Postnatal Depression Scale scores ??10 (8.49%) than women who received  no epidural analgesia (26.42%) (OR, 0.209; 95% CI, 0.096-0.429; P < 0.001). At 42 days postpartum, ?the prevalence of EODS scores > 10 was 6.59% in the epidural analgesia group and 25.16% in the no epidural analgesia group (OR, 0.235; 95% CI, 0.113-0.469; P < 0.001). 

MGH Center for Women's Mental Health