Springer Nature remains neutral with regard to jurisdictional claims in clinifal maps and institutional affiliations. Information from the National Library of Medicine Choosing to participate in a study is an important personal decision. Mediterranean J Cardiol. No study has yet compared men and women metabolic response to diet MedDiet in clinical controlled metabolic context in which all foods and clinical consumed are provided to the participant prepared by the research team. A Mediterranean diet supplemented with either olive oil or nuts is the only dietary intervention that mediterranean been shown to prevent major cardiovascular events in a randomized controlled trial [ 1 ]. Previous Trial Back to results Next Trial. Esposito, showed diet the diet helped reduce insulin resistance, trial feature of trial syndrome and type 2 diabetes 3.
Effects of a Mediterranean diet enriched with virgin olive oil or mixed nuts versus a low fat diet on the primary prevention of cardiovascular disease: a randomised controlled trial. A Mediterranean-style diet enriched with virgin olive oil or mixed nuts prevents cardiovascular events cardiovascular death, non-fatal myocardial infarction, or non-fatal stroke. Not available in web format, please use the contact details to request a patient information sheet. Participants are randomly assigned into three equal groups: 1. Mediterranean-style diet with added virgin olive oil 2.
Study record managers: refer to the Data Element Definitions if submitting registration or results information. Other: Controlled nutritional intervention based on the Mediterranean diet Men are assigned to a 4 weeks isocaloric controlled nutritional intervention based on the Mediterranean diet MedDiet in which all foods and drinks are provided. Habitual energy intake of each participant is established by averaging energy requirements estimated by a validated food-frequency questionnaire FFQ and energy needs as determined by the Harris-Benedict formula. Body weight is measured on weekdays and total energy provided is revised if necessary for minimizing body weight fluctuations. This intervention period is preceded by a 4 weeks uncontrolled run-in period based on the Canada’s Food Guide.